Monosomy 7 in donor cell-derived leukemia after bone marrow transplantation for severe aplastic anemia: Report of a new case and review of the literature

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dc.TypeArticlept_BR
dc.contributor.authorOtero, Luize
dc.contributor.authorSouza, Daiane Corrêa de Souza e
dc.contributor.authorTavares, Rita de Cássia Barbosa da Silva
dc.contributor.authorGomes, Bernadete Evangelho
dc.contributor.authorPadilha, Telma de França
dc.contributor.authorBouzas, Luis Fernando da Silva
dc.contributor.authorFernandez, Teresa de Souza
dc.contributor.authorAbdelhay, Eliana Saul Furquim Werneck
dc.date.accessioned2023-05-25T17:20:03Z
dc.date.available2023-05-25T17:20:03Z
dc.date.issued2012-12
dc.description.abstractMonosomy 7 arises as a recurrent chromosome aberration in donor cell leukemia after hematopoietic stem cell transplantation. We report a new case of donor cell leukemia with monosomy 7 following HLA-identical allogenic bone marrow transplantation for severe aplastic anemia (SAA). The male patient received a bone marrow graft from his sister, and monosomy 7 was detected only in the XX donor cells, 34 months after transplantation. The patient's bone marrow microenvironment may have played a role in the leukemic transformation of the donor hematopoietic cells.pt_BR
dc.identifier.issn1678-4685
dc.identifier.urihttps://ninho.inca.gov.br/jspui/handle/123456789/13939
dc.subjectMonossomiapt_BR
dc.subjectMonosomypt_BR
dc.subjectDoadores de Tecidospt_BR
dc.subjectTissue Donorspt_BR
dc.subjectLeucemia de Células Tpt_BR
dc.subjectLeukemia T-Cellpt_BR
dc.subjectTransplante de Medula Ósseapt_BR
dc.subjectBone Marrow Transplantationpt_BR
dc.subjectAnemia Aplásticapt_BR
dc.subjectAnemia Aplasticpt_BR
dc.subjectDoença Catastróficapt_BR
dc.subjectCatastrophic Illnesspt_BR
dc.titleMonosomy 7 in donor cell-derived leukemia after bone marrow transplantation for severe aplastic anemia: Report of a new case and review of the literaturept_BR

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