Gene therapy access: global challenges, opportunities, and views from Brazil, South Africa, and India

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dc.TypeArticlept_BR
dc.contributor.affilliationDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USApt_BR
dc.contributor.affilliationMolecular Carcinogenesis Program, Research Coordination, National Cancer Institute (INCA), Rio de Janeiro, Brazil; Vice-Presidency of Research and Biological Collections (VPPCB), Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.pt_BR
dc.contributor.affilliationDepartment of Molecular Medicine and Haematology, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.pt_BR
dc.contributor.affilliationSpark Therapeutics, Philadelphia, PA 19104, USA.pt_BR
dc.contributor.affilliationFaculty of Medicine University of Southampton, UK & KJ Somaiya Super Speciality Hospital and Research Centre, Mumbai, India.pt_BR
dc.contributor.affilliationDepartment of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kapur, UP, India.pt_BR
dc.contributor.authorCornetta, Kenneth
dc.contributor.authorBonamino, Martín Hernán
dc.contributor.authorMahlangu, Johnny
dc.contributor.authorMingozzi, Federico
dc.contributor.authorRangarajan, Savita
dc.contributor.authorRao, Jayandharan Giridhara
dc.date.accessioned2023-03-14T19:09:24Z
dc.date.available2023-03-14T19:09:24Z
dc.date.issued2022
dc.descriptionv. 30, n. 6, p. 2122-2129, jun. 2022pt_BR
dc.description.abstractGene and cell therapies for a variety of life-limiting illnesses are under investigation, and a small number of commercial products have successfully obtained regulatory approval. The cost of treatment is high, and clinical studies evaluating safety and efficacy are performed predominately in high-income countries. We reviewed the current status of gene and cell therapies in low- and middle-income countries and highlighted the need and current barriers to access. The state of product development in Brazil, South Africa, and India is discussed, including lessons learned from American Society of Gene and Cell Therapy (ASGCT)-sponsored virtual symposia in each of these countries.pt_BR
dc.identifier.citationCORNETTA, Kenneth; BONAMINO, Martín; MAHLANGU, Johnny; MINGOZZI, Federico; RANGARAJAN, Savita; RAO, Jayandharan. Gene therapy access: global challenges, opportunities, and views from brazil, south africa, and india. Molecular Therapy, [S.L.], v. 30, n. 6, p. 2122-2129, jun. 2022. DOI: http://dx.doi.org/10.1016/j.ymthe.2022.04.002.pt_BR
dc.identifier.issn1525-0016
dc.identifier.urihttps://ninho.inca.gov.br/jspui/handle/123456789/13017
dc.language.isoengpt_BR
dc.publisherMolecular Therapypt_BR
dc.relation.ispartofseriesv. 30;n. 6
dc.subjectTerapia Baseada em Transplante de Células e Tecidospt_BR
dc.subjectCell-and Tissue-Based Therapypt_BR
dc.subjectTratamiento Basado en Trasplante de Células y Tejidospt_BR
dc.subjectTerapia Genéticapt_BR
dc.subjectGenetic Therapypt_BR
dc.titleGene therapy access: global challenges, opportunities, and views from Brazil, South Africa, and Indiapt_BR

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