Multidisciplinary diagnostics of chronic lymphocytic leukemia: European Research Initiative on CLL - ERIC recommendations

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dc.TypeArticlept_BR
dc.contributor.authorD'Andrea, Mariana Gama
dc.contributor.authorMonteiro, Lucia
dc.contributor.authorPimenta, Glicínia
dc.contributor.authorXisto, Beth
dc.contributor.authorRenault, Ilana Zalcberg
dc.date.accessioned2022-04-05T18:02:07Z
dc.date.available2022-04-05T18:02:07Z
dc.date.issued2020-07
dc.description.abstractRecent advances in chronic lymphocytic leukemia (CLL) includes description of disease genomic landscape, inclusion of prognostic relevant genetic tests in CLL workflow and evaluation of minimal residual disease (MRD)1 in parallel with the increase availability of novel therapy agents. In this review, the theoretical and practical aspects of response assessment have been discussed. These are based on updated recommendations of the European Research Initiative on Chronic Lymphocytic Leukemia (ERIC) for genetic tests (TP53 mutation and IGHVstatus) and flow cytometry analysis for CLL. Methodological approaches and interpretation of results were also discussed.pt_BR
dc.identifier.issn2531-1387
dc.identifier.other10.1016/j.htct.2019.07.006
dc.identifier.urihttp://sr-vmlxaph03:8080/jspui/handle/123456789/6259
dc.language.isoenpt_BR
dc.publisherHematology, Transfusion and Cell Therapypt_BR
dc.subjectLeukemia, Lymphocytic, Chronic, B-Cellpt_BR
dc.subjectChronic Lymphocytic Leukemiapt_BR
dc.subjectNeoplasm, Residualpt_BR
dc.subjectMinimal Residual Diseasept_BR
dc.subjectFlow Cytometrypt_BR
dc.subjectTumor Suppressor Protein p53pt_BR
dc.subject.otherDEL(17P)en
dc.subject.otherTP53 mutationsen
dc.subject.otherMutational status of IGHVen
dc.titleMultidisciplinary diagnostics of chronic lymphocytic leukemia: European Research Initiative on CLL - ERIC recommendationspt_BR

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