CD7 +, CD4-/CD8- Acute Leukemia with t(11;14)(p15;q11) in a Child

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dc.TypeArticlept_BR
dc.contributor.authorValente, Aloísio Netto
dc.contributor.authorSilva, Maria Luiza Macedo
dc.contributor.authorOliveira, Maria do Socorro Pombo de
dc.contributor.authorAbdelhay, Eliana Saul Furquim Werneck
dc.contributor.authorBouzas, Luis Fernando da Silva
dc.contributor.authorLaun, Lisselot
dc.contributor.authorRibeiro, Raul Corrêa
dc.date.accessioned2023-05-22T19:05:43Z
dc.date.available2023-05-22T19:05:43Z
dc.date.issued1991-10
dc.description.abstractABSTRACT: A t(ll;14)(p15;q11) was the sale chromosome abnormality observed in the malignant cells of a lO-year-old boy with acute leukemia. Morphologically, these cells were classified as L1 by the criteria of the French-American-British Working Group. Cytochemical analysis revealed that the leukemic cells were negative for Sudan Black B, periodic acid Schiff, and esterases, and positive for acid phosphatase. Immunophenotyping disclosed that the cells expressed a very immature antigenic profile [CD34 +, CD7 +, cytoplasmic CD3 +, membrane CD3 -, CD4 -, and CDS-]. In spite of very intensive chemotherapy, complete remission was never induced, and the child died of progressive disease. The relationship of this case to other reported cases of acute leukemia arising from immature pluripotent hematopoietic cells is discussed.pt_BR
dc.identifier.issn1873-4456
dc.identifier.urihttps://ninho.inca.gov.br/jspui/handle/123456789/13884
dc.subjectAntígenos CD7pt_BR
dc.subjectAntigens CD7pt_BR
dc.subjectAntígenos CD4pt_BR
dc.subjectCD4 Antigenspt_BR
dc.subjectAntígenos CD8pt_BR
dc.subjectCD8 Antigenspt_BR
dc.subjectLeucemia-Linfoma de Células T do Adultopt_BR
dc.subjectLeukemia-Lymphoma Adult T-Cellpt_BR
dc.subjectChromosomes Human Pair 11pt_BR
dc.subjectCromossomos Humanos Par 14pt_BR
dc.subjectChromosomes, Human Pair 14pt_BR
dc.subjectCromossomos Humanos Par 11pt_BR
dc.subjectCriançapt_BR
dc.subjectChildpt_BR
dc.titleCD7 +, CD4-/CD8- Acute Leukemia with t(11;14)(p15;q11) in a Childpt_BR

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