Diffusion tensor magnetic resonance imaging may show abnormalities in the normal-appearing cervical spinal cord from patients with multiple sclerosis

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dc.TypeArticlept_BR
dc.contributor.authorPessôa, Fernanda Miraldi Clemente
dc.contributor.authorLopes, Fernanda Cristina Rueda
dc.contributor.authorCosta, João Victor Altamiro
dc.contributor.authorLeon, Soniza Vieira Alves
dc.contributor.authorGasparetto, Emerson Leandro
dc.date.accessioned2023-04-13T17:36:02Z
dc.date.available2023-04-13T17:36:02Z
dc.date.issued2013
dc.descriptionp. 580-583.: il. color.
dc.description.abstractAbstracts Objective This study aims to evaluate “in vivo” the integrity of the normal-appearing spinal cord (NASC) in patients with multiple sclerosis (MS) compared to controls, using diffusion tensor MR imaging. Methods We studied 32 patients with MS and 17 without any neurologic disorder. Fractional anisotropy (FA), axial diffusivity (AD), radial diffusivity (RD) and mean diffusivity (MD) were calculated within regions of interest at C2 and C7 levels in the four columns of the spinal cord. Results At C2, FA value was decreased in MS patients. Besides, RD value was higher in MS than in controls. At C7, MD values were increased in MS. Conclusion The NASC in the right column of the cervical spinal cord showed abnormal FA, RD and MD values, which is possibly related to demyelination, since the FA abnormality was related to the RD and not to the AD. diffusion tensor imaging; multiple sclerosis; cervical spinal cord.pt_BR
dc.identifier.citationPESSÔA, Fernanda Miraldi Clemente et al. Diffusion tensor magnetic resonance imaging may show abnormalities in the normal-appearing cervical spinal cord from patients with multiple sclerosis. Diffusion tensor MR, p. 580-583, set. 2013.
dc.identifier.issn1678-4227
dc.identifier.urihttps://ninho.inca.gov.br/jspui/handle/123456789/13601
dc.publisherDiffusion tensor MR
dc.subjectImagem de Tensor de Difusãopt_BR
dc.subjectDiffusion Tensor Imagingpt_BR
dc.subjectEsclerose Múltiplapt_BR
dc.subjectMultiple Sclerosispt_BR
dc.subjectMedula Cervicalpt_BR
dc.subjectCervical Cordpt_BR
dc.terms.abstractObjetivo: Este estudo avalia “in vivo” a integridade da medula espinhal cervical aparentemente normal (MEAN) em pacientes com esclerose múltipla (EM) comparados aos controles, usando a imagem por tensor de difusão. Métodos: Foram selecionados 32 pacientes com EM e 17 controles. Foram calculadas fração anisotrópica (FA), difusão axial (DA), difusão radial (DR) e difusibilidade média (DM) dentro das regiões de interesse nos níveis C2 e C7 nas quatro colunas da medula espinhal. Resultados: Em C2, o valor de FA foi reduzido em pacientes com EM. Além disso, o valor da DR se mostrou mais elevado na EM do que nos controles. Em C7, os valores de MD foram maiores na EM. Conclusão: A MEAN na coluna direita da medula cervical mostrou valores alterados de FA, RD e MD, possivelmente relacionados à desmielinização, uma vez que a alteração de FA está relacionada à DR e não à DA.pt_BR
dc.titleDiffusion tensor magnetic resonance imaging may show abnormalities in the normal-appearing cervical spinal cord from patients with multiple sclerosispt_BR
dc.title.alternativeExames de imagem por tensor de difusão podem mostrar alterações na coluna cervical aparentemente normal em pacientes com esclerose múltiplapt_BR

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