Clinical and Molecular Properties of Human Immunodeficiency Virus-Related Diffuse Large B-Cell Lymphoma

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dc.TypeArticlept_BR
dc.contributor.authorCarvalho, Pedro Santos de
dc.contributor.authorLeal, Fabio Eudes
dc.contributor.authorSoares, Marcelo Alves
dc.date.accessioned2022-06-10T13:58:23Z
dc.date.available2022-06-10T13:58:23Z
dc.date.issued2021
dc.description.abstractNon-Hodgkin lymphoma is the most common malignancy affecting people living with HIV (PLWH). Among its several subtypes, diffuse large B-cell lymphoma (DLBCL) is an important manifestation within the HIV-infected compartment of the population. Since HIV is able to modulate B cells and promote lymphomagenesis through direct and indirect mechanisms, HIV-related DLBCL has specific characteristics. In this review, we address the clinical and molecular properties of DLBCL disease in the context of HIV infection, as well as the mechanisms by which HIV is able to modulate B lymphocytes and induce their transformation into lymphoma.pt_BR
dc.identifier.issn2234-943X
dc.identifier.other10.3389/fonc.2021.675353
dc.identifier.urihttp://sr-vmlxaph03:8080/jspui/handle/123456789/7386
dc.language.isoenpt_BR
dc.publisherFrontiers in Oncologypt_BR
dc.subjectLymphoma, Non-Hodgkinpt_BR
dc.subjectLinfoma não Hodgkinpt_BR
dc.subjectLinfoma no Hodgkinpt_BR
dc.subjectLymphoma, Large B-Cell, Diffusept_BR
dc.subjectLinfoma Difuso de Grandes Células Bpt_BR
dc.subjectLinfoma de Células B Grandes Difusopt_BR
dc.subjectDiffuse Large B-Cell Lymphomapt_BR
dc.subjectLinfoma Difuso de Células B Grandespt_BR
dc.subjectHIVpt_BR
dc.subject.otherActivated B-Likeen
dc.subject.otherGerminal Center B-likeen
dc.subject.otherPeople Living With HIVen
dc.titleClinical and Molecular Properties of Human Immunodeficiency Virus-Related Diffuse Large B-Cell Lymphomapt_BR

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