https://ninho.inca.gov.br/jspui/handle/123456789/5107 Coleção voltada para a inserção de documentos da área de Divisão Médica Wed, 08 Apr 2026 09:05:16 GMT 2026-04-08T09:05:16Z https://ninho.inca.gov.br/jspui/handle/123456789/15703 Title: Produção de material educativo sobre câncer de mama e câncer do colo do útero compartilhada com o movimento organizado de mulheres: construindo uma perspectiva de gênero Authors: Santos, Maria do Espírito Santo Tavares dos; Claro, Itamar Bento; Bortolon, Paula Chagas; Assis, Mônica de; Silva, Marcos André Félix da; Ramos, Danielle Nogueira; Vieira, Marcos Fábio; Dias, Maria Beatriz Kneipp Abstract: A experiência de produção compartilhada com lideranças feministas para atualização de folderes sobre câncer de mama e câncer do colo do útero. Perspectiva de incorporar demandas e necessidades das mulheres, na perspectiva de gênero. Description: 11 p.: il. color. Thu, 01 Jan 2015 00:00:00 GMT https://ninho.inca.gov.br/jspui/handle/123456789/15703 2015-01-01T00:00:00Z https://ninho.inca.gov.br/jspui/handle/123456789/15687 Title: Técnica cirúrgica , resultados fonatórios e complicações em pacientes submetidos a reabilitação vocal com prótese traqueo-esofágica Authors: Vital, Juliana Maria de Almeida; Santos, Izabella Costa; Freitas, Emilson de Queiroz; Quintanilha, Marina Azzi; Siebra, Paulo José Cavalcanti; Botinelly, Ruiter Diego Moraes; Oliveira, Daniela Rocha Batista de; Freitas, Andressa Silva de Description: 13 p.: il. color. Thu, 01 Jan 2015 00:00:00 GMT https://ninho.inca.gov.br/jspui/handle/123456789/15687 2015-01-01T00:00:00Z https://ninho.inca.gov.br/jspui/handle/123456789/5400 Title: Osteopontin-c Splicing Isoform Contributes to Ovarian Cancer Progression Authors: Tilli, Tatiana Martins; Franco, Vanessa Ferreira; Robbs, Bruno Kaufmann; Wanderley, Joao Luiz Mendes; Silva, Fabrício Ribeiro de Azevedo da; Mello, Kivvi Duarte de; Viola, Joao Paulo de Biaso; Weber, Georg Franz; Gimba, Etel Rodrigues Pereira Abstract: Ovarian carcinoma is one of the most aggressive gynecological diseases and generally diagnosed at advanced stages. Osteopontin (OPN) is one of the proteins overexpressed in ovarian cancer and is involved in tumorigenesis and metastasis. Alternative splicing of OPN leads to 3 isoforms, OPNa, OPNb, and OPNc. However, the expression pattern and the roles of each of these isoforms have not been previously characterized in ovarian cancer. Herein, we have evaluated the expression profiling of OPN isoforms in ovarian tumor and nontumor samples and their putative roles in ovarian cancer biology using in vitro and in vivo functional assays. OPNa and OPNb were expressed both in tumor and nontumor ovarian samples, whereas OPNc was specifically expressed in ovarian tumor samples. The isoform OPNc significantly activated OvCar-3 cell proliferation, migration, invasion, anchorage-independent growth and tumor formation in vivo. Additionally, we have also shown that some of the OPNc-dependent protumorigenic roles are mediated by PI3K/Akt signaling pathway. OPNc stimulated immortalized ovarian epithelial IOSE cell proliferation, indicating a role for this isoform in ovarian cancer tumorigenesis. Functional assays using OPNc conditioned medium and an anti-OPNc antibody have shown that most cellular effects observed herein were promoted by the secreted OPNc. According to our data, OPNc-specific expression in ovarian tumor samples and its role on favoring different aspects of ovarian cancer progression suggest that secreted OPNc contributes to the physiopathology of ovarian cancer progression and tumorigenesis. Altogether, the data open possibilities of new therapeutic approaches for ovarian cancer that selectively down regulate OPNc, altering its properties favoring ovarian tumor progression Description: p. 280-293.: il. p&b. Sat, 01 Jan 2011 00:00:00 GMT https://ninho.inca.gov.br/jspui/handle/123456789/5400 2011-01-01T00:00:00Z https://ninho.inca.gov.br/jspui/handle/123456789/5323 Title: Transfusion medicine in medical education: an analysis of curricular grids in Brazil and a review of the current literature Authors: Vaena, Marcella Martins de Vasconcelos; Alves, Luiz Anastacio; Almeida, Vinicius Cotta de Abstract: Blood transfusions are one of the most performed medical procedures in the world. Thus, as education in transfusion medicine is vital to medical care, it should aim to promote a responsible practice with the rational use of blood by doctors. This study aims to investigate the situation of the teaching of transfusion medicine in medical schools in Brazil. Method: The websites of the 249 Brazilian medical schools in operation in June 2015 were visited and the curricula of the medical courses were investigated in respect to the presence or absence of a transfusion medicine discipline. When available, the subject grids were analyzed to verify whether a description of content regarding transfusion medicine was given within other disciplines. Results: Of the 249 medical school sites visited, information on the curriculum was obtained from 178. Of the medical schools that published their curriculum, 132 (74.1%) did not have disciplines of transfusion medicine or hematology and only seven (3.9%) had a discipline of transfusion medicine in the curricular grid. Conclusions: Education on transfusion medicine is of fundamental importance for safe and efficient transfusion practices. Deficiencies in medical knowledge of this subject have been found worldwide. The results of this study indicate a possible deficiency in teaching the basics of this specialty. Thus, additional prospective studies to assess the knowledge and practice of transfusion medicine in Brazilian medical schools are warranted, which could prompt a discussion on the importance of offering training in transfusion medicine to medical students. Description: p. 252-256.: il. color. Fri, 01 Jan 2016 00:00:00 GMT https://ninho.inca.gov.br/jspui/handle/123456789/5323 2016-01-01T00:00:00Z