Naphthoquinone-based chalcone hybrids and derivatives: synthesis and potent activity against cancer cell lines
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Date
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Journal ISSN
Volume Title
Publisher
Medicinal Chemistry Communications
Abstract
Novel naphthoquinone-based chalcones were prepared from the reaction between 3-bromo-nor-blapachone and amino-chalcones. Lapachone derivatives are also described here. All the substances were
evaluated against cancer and normal cell lines and several compounds demonstrated potent antitumor
activity.
Description
p. 120–130.: il. p&b.
Keywords
Citation
JARDIM, Guilherme Augusto de Melo et al. Naphthoquinone-based chalcone hybrids and derivatives: synthesis and potent activity against cancer cell lines. Medicinal Chemistry Communications, v. 6, p. 120–130, 2015.