Naphthoquinone-based chalcone hybrids and derivatives: synthesis and potent activity against cancer cell lines

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dc.TypeArticlept_BR
dc.contributor.authorJardim, Guilherme Augusto de Melo
dc.contributor.authorPinto, Maria do Carmo Freire Ribeiro
dc.contributor.authorFarias, Kaio Moraes de
dc.contributor.authorPessoa, Claudia do Ó
dc.contributor.authorGatto, Claudia Cristina
dc.contributor.authorNair, Divya knairdivya
dc.contributor.authorNamboothiri, Irishi Narayanan Narayanan
dc.contributor.authorSilva Júnior, Eufrânio Nunes da
dc.contributor.authorCavalcanti, Bruno Coelho
dc.contributor.authorGuimarães, Tiago Teixeira
dc.date.accessioned2022-07-04T19:11:26Z
dc.date.available2022-07-04T19:11:26Z
dc.date.issued2015
dc.descriptionp. 120–130.: il. p&b.
dc.description.abstractNovel naphthoquinone-based chalcones were prepared from the reaction between 3-bromo-nor-blapachone and amino-chalcones. Lapachone derivatives are also described here. All the substances were evaluated against cancer and normal cell lines and several compounds demonstrated potent antitumor activity.
dc.identifier.citationJARDIM, Guilherme Augusto de Melo et al. Naphthoquinone-based chalcone hybrids and derivatives: synthesis and potent activity against cancer cell lines. Medicinal Chemistry Communications, v. 6, p. 120–130, 2015.
dc.identifier.urihttp://sr-vmlxaph03:8080/jspui/handle/123456789/8586
dc.publisherMedicinal Chemistry Communicationspt_BR
dc.subjectChalconapt_BR
dc.subjectChalconept_BR
dc.subjectNaftoquinonaspt_BR
dc.subjectNaphthoquinonespt_BR
dc.subjectCélulaspt_BR
dc.subjectCellspt_BR
dc.subjectNeoplasiaspt_BR
dc.subjectNeoplasmspt_BR
dc.titleNaphthoquinone-based chalcone hybrids and derivatives: synthesis and potent activity against cancer cell linespt_BR

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