Please use this identifier to cite or link to this item: https://ninho.inca.gov.br/jspui/handle/123456789/13899
Title: Cytogenetic analysis of 100 consecutive newly diagnosed cases of acute lymphoblastic leukemia in Rio de Janeiro
Authors: Silva, Maria Luiza Macedo
Souza, Maria Helena Ornellas de
Ribeiro, Raul Corrêa
Land, Marcelo Gerardin Poirot
Azevedo, Alice Maria Boulhosa de
Vasconcelos, Felippe
Otero, Luize
Vasconcelos, Zilton Farias Meira de
Bouzas, Luis Fernando da Silva
Abdelhay, Eliana Saul Furquim Werneck
Keywords: Citogenética
Cytogenetics
Diagnóstico Clínico
Clinical Diagnosis
Leucemia-Linfoma Linfoblástico de Células Precursoras
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Issue Date: 2002
Abstract: We report the cytogenetic analysis of newly diagnosed Brazilian children with acute lymphocytic leuke mia (ALL). We investigated 100 ALL cases from four different institutions in Rio de Janeiro. The fre quency of chromosomal abnormalities was 92.3%. The karyotype profile and recurrent abnormalities found in this study do not differ essentially from those described by other groups. Although the Brazilian population is usually the product of different ethnic groups, our results show that the frequency of each re current abnormality is similar to that found in populations without our degree of diverse ethnic composi tion. Hence, our results suggest that childhood ALL in Brazil has the same biological features as that in developed countries, supporting the use of similar treatment protocols. We can therefore expect to reach the same survival rates in the coming years, depending possibly on the efficacy of the support therapy and extent of social assistance.
URI: https://ninho.inca.gov.br/jspui/handle/123456789/13899
ISSN: 1873-4456
Appears in Collections:Hospital do Câncer I (HCI)



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