Please use this identifier to cite or link to this item: https://ninho.inca.gov.br/jspui/handle/123456789/5331
Title: The effect of addition of chemotherapy to radiotherapy in the treatment of women with cervical cancer: a survival analysis using propensity score
Authors: Carmo, Claudio Calazan do
Luiz, Ronir Raggio
Silva, Gustavo
Keywords: Neoplasias do Colo do Útero
Uterine Cervical Neoplasms
Epidemiologia
Epidemiology
Survival analysis
Análise de Sobrevida
Radioterapia
Radiotherapy
Tratamento Farmacológico
Drug Therapy
Issue Date: 2008
Publisher: Gynecologic Oncology
Citation: CARMO, Claudio Calazan do; LUIZ, Ronir Raggio; SILVA, Gustavo. The effect of addition of chemotherapy to radiotherapy in the treatment of women with cervical cancer: a survival analysis using propensity score. Gynecologic Oncology, v. 111, p. 271 – 275, 2008.
Abstract: To compare the overall survival of patients with cervical cancer treated exclusively with radiotherapy with that of patients treated with a combination of radio and chemotherapy. Material and methods. Retrospective analysis of all cases of cervical cancer registered at the Brazilian National Cancer Institute between 1999 and 2004, treated with radiotherapy exclusively or in combination with chemotherapy. The Kaplan–Meier curve and the log-rank test were used to assess overall survival. The Cox model and the propensity score were used for multivariate analysis. Results. A total of 2584 patients were studied, and the clinical and epidemiological characteristics of the cohort were described. The combination of chemotherapy with radiotherapy provided an improvement in survival when compared with radiotherapy exclusively (HR-0.69; pb0.001), which persisted after multivariate analysis (HR-0.72; pb0.001). Conclusion. There was a beneficial effect of adding chemotherapy to radiotherapy on this cohort.
Description: p. 271–275.: tab. p&b.
URI: http://sr-vmlxaph03:8080/jspui/handle/123456789/5331
ISSN: 0090-8258
Appears in Collections:Artigos de Periódicos da área de Oncologia Clínica



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