Please use this identifier to cite or link to this item: https://ninho.inca.gov.br/jspui/handle/123456789/5424
Title: Methicillin-resistant Staphylococcus aureus in Rio de Janeiro hospitals: Dissemination of the USA400/ST1 and USA800/ST5 SCCmec type IV and USA100/ST5 SCCmec type II lineages in a public institution and polyclonal presence in a private one
Authors: Caboclo, Roberta Mello Ferreira
Cavalcante, Fernanda Sampaio
Iorio, Natalia Lopes Pontes
Schuenck, Ricardo Pinto
Olendzki, André Nogueira
Felix, Maria José
Chamon, Raiane Cardoso
Santos, Kátia Regina Netto dos
Keywords: Staphylococcus aureus Resistente à Meticilina
Methicillin-Resistant Staphylococcus aureus
Testes de Sensibilidade Microbiana
Microbial Sensitivity Tests
Linhagem da Célula
Cell Lineage
Eletroforese em Gel de Campo Pulsado
Electrophoresis Gel Pulsed-Field
Stenotrophomonas maltophilia
Hospitals Private
Hospitais Privados
Hospitais Públicos
Hospitals Public
Issue Date: 2013
Publisher: American Journal of Infection Control
Citation: CABOCLO, Roberta Mello Ferreira et al. Methicillin-resistant Staphylococcus aureus in Rio de Janeiro hospitals: Dissemination of the USA400/ST1 and USA800/ST5 SCCmec type IV and USA100/ST5 SCCmec type II lineages in a public institution and polyclonal presence in a private one. American Journal of Infection Control, v. 41, p. 21-26, 2013.
Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) infections have changed since certain non-multiresistant MRSA lineages have emerged in hospitals. In this study, 99 MRSA isolates, 77 from a public and 22 from a private hospital, were characterized. Methods: Isolates were tested for antimicrobial susceptibility, whereas staphylococcal chromosomal cassette mec (SCCmec) typing and Panton-Valentine leukocidin genes were assessed by polymerase chain reaction. Pulsed-field gel electrophoresis and multilocus sequence typing analyses were carried out to determine the MRSA lineages. Results: High rates of resistance were found to erythromycin (96%), ciprofloxacin (93%), and clindamycin (90%). The SCCmec types found were as follows: type II (14.2%), III (62.6%), and IV (23.2%). Approximately 85% of type III isolates was related to the Brazilian epidemic clone in both hospitals. For type IV isolates, 94.4% were related to both USA400/ sequence type (ST) 1 and USA800/ST5 lineages in the public hospital, whereas the USA400/ST1, USA800/ST5, USA1100/ST30, and EMRSA (Epidemic MRSA)-15/ST22 lineages were detected in the private hospital. Among the SCCmec II isolates, approximately 85% were related to the USA100/ST5 lineage. Three MRSA isolates were positive to Panton-Valentine leukocidin genes. Conclusion: The study showed that there was an emergence of USA400/ST1, USA800/ST5 SCCmec IV, and USA100/ST5 SCCmec II MRSA lineages in both hospitals. There was a dissemination of them in the public hospital and a polyclonal presence of the MRSA isolates in the private hospital. The spread of these lineages can be facilitated by the characteristics of the health institution.
Description: p. 21-26.: il. p&b.
URI: http://sr-vmlxaph03:8080/jspui/handle/123456789/5424
ISSN: 0196-6553
Appears in Collections:Artigos de Periódicos da área de Farmácia

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