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Please use this identifier to cite or link to this item: https://ninho.inca.gov.br/jspui/handle/123456789/6259
Title: Multidisciplinary diagnostics of chronic lymphocytic leukemia: European Research Initiative on CLL - ERIC recommendations
Authors: D'Andrea, Mariana Gama
Monteiro, Lucia
Pimenta, Glicínia
Xisto, Beth
Renault, Ilana Zalcberg
Keywords: Leukemia, Lymphocytic, Chronic, B-Cell
Chronic Lymphocytic Leukemia
Neoplasm, Residual
Minimal Residual Disease
Flow Cytometry
Tumor Suppressor Protein p53
Issue Date: Jul-2020
Publisher: Hematology, Transfusion and Cell Therapy
Abstract: Recent advances in chronic lymphocytic leukemia (CLL) includes description of disease genomic landscape, inclusion of prognostic relevant genetic tests in CLL workflow and evaluation of minimal residual disease (MRD)1 in parallel with the increase availability of novel therapy agents. In this review, the theoretical and practical aspects of response assessment have been discussed. These are based on updated recommendations of the European Research Initiative on Chronic Lymphocytic Leukemia (ERIC) for genetic tests (TP53 mutation and IGHVstatus) and flow cytometry analysis for CLL. Methodological approaches and interpretation of results were also discussed.
URI: http://sr-vmlxaph03:8080/jspui/handle/123456789/6259
ISSN: 2531-1387
Appears in Collections:Artigo de Periódicos da Pesquisa Clínica

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