Please use this identifier to cite or link to this item: https://ninho.inca.gov.br/jspui/handle/123456789/7457
Title: Acute Effects of Continuous Positive Air way Pressure on Pulse Pressure in Chronic Heart Failure
Authors: Quintão, Mônica Maria Pena
Chermont, Sergio Luiz Soares Marcos da Cunha
Marchese, Luana
Brandão, Lúcia
Mesquita, Evandro Tinoco
Rocha, Nazareth de Novaes
Nóbrega, Antônio Claudio Lucas da
Pereira, Sabrina Bernardez
Keywords: Insuficiência Cardíaca
Heart Failure
Pressão Sanguínea
Blood Pressure
Pressão Positiva Contínua nas Vias Aéreas
Continuous Positive Airway Pressure
Issue Date: 2014
Publisher: Arq Bras Cardiol
Citation: QUINTÃO, Mônica Maria Pena et al. Acute Effects of Continuous Positive Air way Pressure on Pulse Pressure in Chronic Heart Failure. Arq Bras Cardiol., v. 102, n. 2, p. 181-186, feb. 2014.
Abstract: Patients with heart failure (HF) have left ventricular dysfunction and reduced mean arterial pressure (MAP). Increased adrenergic drive causes vasoconstriction and vessel resistance maintaining MAP, while increasing peripheral vascular resistance and conduit vessel stiffness. Increased pulse pressure (PP) reflects a complex interaction of the heart with the arterial and venous systems. Increased PP is an important risk marker in patients with chronic HF (CHF). Non invasive ventilation (NIV) has been used for acute decompensated HF, to improve congestion and ventilation through both respiratory and hemodynamic effects. However, none of these studies have reported the effect of NIV on PP. Objective: The objective of this study was to determine the acute effects of NIV with CPAP on PP in outpatients with CHF. Methods: Following a double-blind, randomized, cross-over, and placebo-controlled protocol, twenty three patients with CHF (17 males; 60 ± 11 years; BMI 29 ± 5 kg/cm2 , NYHA class II, III) underwent CPAP via nasal mask for 30 min in a recumbent position. Mask pressure was 6 cmH2 O, whereas placebo was fixed at 0-1 cmH2 O. PP and other non invasive hemodynamics variables were assessed before, during and after placebo and CPAP mode. Results: CPAP decreased resting heart rate (Pre: 72 ± 9; vs. Post 5 min: 67 ± 10 bpm; p < 0.01) and MAP (CPAP: 87 ± 11; vs. control 96 ± 11 mmHg; p < 0.05 post 5 min). CPAP decreased PP (CPAP: 47 ± 20 pre to 38 ± 19 mmHg post; vs. control: 42 ± 12 mmHg, pre to 41 ± 18 post p < 0.05 post 5 min). Conclusion: NIV with CPAP decreased pulse pressure in patients with stable CHF. Future clinical trials should investigate whether this effect is associated with improved clinical outcome.
Description: p. 181-186.: il. p&b.
URI: http://sr-vmlxaph03:8080/jspui/handle/123456789/7457
ISSN: 1678-4170
Appears in Collections:Artigos de Periódicos da área de Fisioterapia

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