Please use this identifier to cite or link to this item: https://ninho.inca.gov.br/jspui/handle/123456789/8252
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dc.contributor.authorPoça, Katia Soares da-
dc.contributor.authorGiardini, Isabela-
dc.contributor.authorSilva, Paula Vieira Baptista da-
dc.contributor.authorGeraldino, Barbara Rodrigues-
dc.contributor.authorBellomo, Antonella-
dc.contributor.authorAlves, Julia Araújo-
dc.contributor.authorConde, Taline Ramos-
dc.contributor.authorZamith, Helena Pereira da Silva-
dc.contributor.authorOtero, Ubirani Barros-
dc.contributor.authorFerraris, Fausto Klabund-
dc.contributor.authorFriedrich, Karen-
dc.contributor.authorMello, Marcia Sarpa de Campos-
dc.date.accessioned2022-06-30T15:00:23Z-
dc.date.available2022-06-30T15:00:23Z-
dc.date.issued2021-
dc.identifier.citationPOÇA, Katia Soares da et al. Gasoline-station workers in Brazil: Benzene exposure; Genotoxic and immunotoxic effects, Mutation Research/Genetic Toxicology and Environmental Mutagenesis, v. 865, 2021. ISSN 1383-5718. Disponível em: https://doi.org/10.1016/j.mrgentox.2021.503322.pt_BR
dc.identifier.issn1383-5718-
dc.identifier.urihttp://sr-vmlxaph03:8080/jspui/handle/123456789/8252-
dc.descriptionv. 1, 9 p.: il. color.pt_BR
dc.description.abstractChronic exposure to benzene is a risk factor for hematological malignancies. Gasoline-station workers are exposed to benzene in gasoline, via both inhalation and dermal contact (attendants and managers) or inhalation (workers in the on-site convenience stores and offices). We have studied the exposure of these workers to benzene and the resulting genotoxic and immunotoxic effects. Levels of urinary trans, trans-muconic acid were higher among gasoline-station workers than among office workers with no known exposure to benzene (com-parison group). Among the exposed workers, we observed statistically significant biological effects, including elevated DNA damage (comet assay); higher frequencies of micronuclei and nuclear buds (CBMN assay); lower levels of T-helper lymphocytes and naive Th lymphocytes; lower CD4 / CD8 ratio; and higher levels of NK cells and memory Th lymphocytes. Both groups of exposed workers (inhalation and inhalation + dermal routes) showed similar genotoxic and immunotoxic effects.pt_BR
dc.language.isoen_USpt_BR
dc.publisherMutation Research - Genetic Toxicology and Environmental Mutagenesis (MRGTEM)pt_BR
dc.subjectExposição Ocupacionalpt_BR
dc.subjectOccupational Exposurept_BR
dc.subjectExposición Profesionalpt_BR
dc.subjectExposição por Inalaçãopt_BR
dc.subjectInhalation Exposurept_BR
dc.subjectExposición por Inhalaciónpt_BR
dc.subjectBenzenopt_BR
dc.subjectBenzenept_BR
dc.subjectBencenopt_BR
dc.subjectPosto de Combustívelpt_BR
dc.subjectFilling Stationpt_BR
dc.subjectGasolineraspt_BR
dc.subjectDano ao DNApt_BR
dc.subjectDNA Damagept_BR
dc.subjectDaño del ADNpt_BR
dc.titleGasoline-station workers in Brazil: benzene exposure; Genotoxic and immunotoxic effectspt_BR
dc.TypeArticlept_BR
Appears in Collections:Artigos de Periódicos da área da Vigilância do Câncer Relacionado ao Trabalho e ao Ambiente
Marcia Sarpa de Campos Mello

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