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https://ninho.inca.gov.br/jspui/handle/123456789/8586| Title: | Naphthoquinone-based chalcone hybrids and derivatives: synthesis and potent activity against cancer cell lines |
| Authors: | Jardim, Guilherme Augusto de Melo Pinto, Maria do Carmo Freire Ribeiro Farias, Kaio Moraes de Pessoa, Claudia do Ó Gatto, Claudia Cristina Nair, Divya knairdivya Namboothiri, Irishi Narayanan Narayanan Silva Júnior, Eufrânio Nunes da Cavalcanti, Bruno Coelho Guimarães, Tiago Teixeira |
| Keywords: | Chalcona Chalcone Naftoquinonas Naphthoquinones Células Cells Neoplasias Neoplasms |
| Issue Date: | 2015 |
| Publisher: | Medicinal Chemistry Communications |
| Citation: | JARDIM, Guilherme Augusto de Melo et al. Naphthoquinone-based chalcone hybrids and derivatives: synthesis and potent activity against cancer cell lines. Medicinal Chemistry Communications, v. 6, p. 120–130, 2015. |
| Abstract: | Novel naphthoquinone-based chalcones were prepared from the reaction between 3-bromo-nor-blapachone and amino-chalcones. Lapachone derivatives are also described here. All the substances were evaluated against cancer and normal cell lines and several compounds demonstrated potent antitumor activity. |
| Description: | p. 120–130.: il. p&b. |
| URI: | http://sr-vmlxaph03:8080/jspui/handle/123456789/8586 |
| Appears in Collections: | Artigos de Periódicos da área de Farmácia |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Naphthoquinone-based chalcone hybrids and derivatives synthesis and potent activity against cancer cell lines..pdf | 738.28 kB | Adobe PDF | View/Open |
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