Please use this identifier to cite or link to this item:
https://ninho.inca.gov.br/jspui/handle/123456789/12657| Title: | Point-of-care Arkansas method for measuring adherence to treatment with isoniazid |
| Authors: | Guerra, Renata Leborato Conde, Marcus Barreto Efron, Anne Loredo, Carla Bastos, Gisele Chaisson, Richard Ernest Golub, Jonathan Eric |
| Keywords: | Tuberculose Latente Latent Tuberculosis Infecções Infections Isoniazida Isoniazid Arkansas method Método Arkansas Aderência Bacteriana Bacterial Adhesion |
| Issue Date: | May-2010 |
| Publisher: | Respiratory Medicine |
| Abstract: | We evaluated the accuracy of a point-of-care test designed to measure adherence to isoniazid (INH) preventive therapy in a hospital setting in Rio de Janeiro, Brazil. Patients on treatment with daily INH and patients not receiving INH were included. Sensitivity and specificity of the test were 84%/98% at the first minute, and 95%/98% at the fifth minute, respectively. Among smokers, sensitivity and specificity was reduced (80%/89% at the fifth minute, respectively), but only 17% smoked. This test accurately detected INH metabolites 24 h following directly observed INH intake, though sensitivity and specificity may be compromised by tobacco smoke exposure. |
| URI: | https://ninho.inca.gov.br/jspui/handle/123456789/12657 |
| ISSN: | 0954-6111 |
| Appears in Collections: | Artigos de Periódicos da área de Pesquisa Populacional |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Point-of-care Arkansas method for measuring adherence to treatment with isoniazid..pdf | 119.71 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.