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https://ninho.inca.gov.br/jspui/handle/123456789/12661| Title: | Specimen Dilution Improves Sensitivity of the Amplified Mycobacterium tuberculosis Direct Test for Smear Microscopy-Positive Respiratory Specimens |
| Authors: | Guerra, Renata Leborato Baker, James F. Alborz, Roya Armstrong, Derek T. Kiehlbauch, Julia A. Conde, Marcus Barreto Dorman, Susan E. Hooper, Nancy M. |
| Keywords: | Técnicas de Diagnóstico Molecular Molecular Diagnostic Techniques Valor Preditivo dos Testes Predictive Value of Tests Sensibilidade e Especificidade Sensitivity and Specificity Tuberculose Tuberculosis |
| Issue Date: | Jan-2008 |
| Publisher: | Journal of Clinical Microbiology |
| Abstract: | Specimen dilution has been proposed as a strategy to minimize amplified Mycobacterium tuberculosis direct (MTD) test inhibition (N. Pollock, J. Westerling, and A. Sloutsky, Am. J. Clin. Pathol. 126:142-147, 2006; A. Sloutsky, L. L. Han, and B. G. Werner, J. Clin. Microbiol. 42:1547-1551, 2004). We evaluated the impact of respiratory specimen dilution on MTD test accuracy in a public health laboratory. The difference in MTD test sensitivity between the dilution and conventional methods was 15.9% (P = 0.001) for smear microscopy-positive specimens and -3.6% (P = 0.38) for smear microscopy-negative specimens. |
| URI: | https://ninho.inca.gov.br/jspui/handle/123456789/12661 |
| ISSN: | 1098-660X |
| Appears in Collections: | Artigos de Periódicos da área de Pesquisa Populacional |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Specimen Dilution Improves Sensitivity of the Amplified Mycobacterium tuberculosis Direct Test for Smear Microscopy-Positive Respiratory Specimens..pdf | 47.7 kB | Adobe PDF | View/Open |
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