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https://ninho.inca.gov.br/jspui/handle/123456789/13305| Title: | Organ preservation and oncological outcomes in early laryngeal cancer: a propensity score-based study |
| Authors: | Carvalho, Genival Barbosa de Kohler, Hugo Fontan Mello, Julia Bette Homem de Lira, Renan Bezerra Pellizzon, Antonio Cássio de Assis Vartanian, José Guilherme Kowalski, Luiz Paulo Head and Neck Surgery and Otorhinolaryngology Department, A. C. Camargo Cancer Center, São Paulo, Brazil. Carcinogenesis Molecular Program, National Institute of Cancer - INCA, Rio de Janeiro, RJ, Brazil. Radiation Oncology Department, A. C. Camargo Cancer Center, São Paulo, Brazil. Head and Neck Surgery Department and LIM 28, University of Sao Paulo Medical School, Sao Paulo, Brazil. |
| Keywords: | Neoplasias Laríngeas LaryngealNeoplasms Neoplasias Laríngeas Radioterapia Radiotherapy Preservação de Órgãos Organ Preservation Preservación de Órganos |
| Issue Date: | 2021 |
| Publisher: | Acta Otorhinolaryngologica Italica |
| Citation: | CARVALHO, Genival Barbosa de; KOHLER, Hugo Fontan; MELLO, Julia Bette Homem de; LIRA, Renan Bezerra; PELLIZZON, Antonio Cássio de Assis; VARTANIAN, José Guilherme; KOWALSKI, Luiz Paulo. Organ preservation and oncological outcomes in early laryngeal cancer: a propensity score-based study. Acta Otorhinolaryngologica Italica, [S.L.], v. 41, n. 4, p. 317-326, ago. 2021. DOI: http://dx.doi.org/10.14639/0392-100x-n0870. |
| Abstract: | Background: The rates of laryngeal preservation according to therapeutic modality in patients with initial laryngeal squamous cell carcinoma (LSCC) are still controversial. This study evaluated the rates of laryngeal preservation in patients who underwent treatment with surgery or radiotherapy. Methods: This retrospective cohort study evaluated 151 patients with stage I or II LSCC. Ninety-six patients were matched using a propensity-score and outcomes were compared within this group. Results: Regarding overall, cancer-specific survival and larynx preservation, no differences were observed according to the therapeutic modalities, but patients who underwent radiotherapy had a higher rate of local recurrence than those who underwent surgery. Patients classified as ASA 3 or 4 and treated with radiotherapy showed a tendency of higher risk of larynx loss. Conclusions: Patients with stage I or II laryngeal tumours can be submitted to surgery or radiotherapy with similar rates of laryngeal preservation. |
| Description: | v. 41, n. 4, p. 317-326, ago. 2021. |
| URI: | https://ninho.inca.gov.br/jspui/handle/123456789/13305 |
| ISSN: | 0392-100x (Impresso) 1827-675X (Online) |
| Appears in Collections: | Artigo de Periódicos da Pesquisa Clínica |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Organ preservation and oncological outcomes in early laryngeal cancer - a propensity score-based study - 2021.pdf | 2.18 MB | Adobe PDF | View/Open |
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