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https://ninho.inca.gov.br/jspui/handle/123456789/13884| Title: | CD7 +, CD4-/CD8- Acute Leukemia with t(11;14)(p15;q11) in a Child |
| Authors: | Valente, Aloísio Netto Silva, Maria Luiza Macedo Oliveira, Maria do Socorro Pombo de Abdelhay, Eliana Saul Furquim Werneck Bouzas, Luis Fernando da Silva Laun, Lisselot Ribeiro, Raul Corrêa |
| Keywords: | Antígenos CD7 Antigens CD7 Antígenos CD4 CD4 Antigens Antígenos CD8 CD8 Antigens Leucemia-Linfoma de Células T do Adulto Leukemia-Lymphoma Adult T-Cell Chromosomes Human Pair 11 Cromossomos Humanos Par 14 Chromosomes, Human Pair 14 Cromossomos Humanos Par 11 Criança Child |
| Issue Date: | Oct-1991 |
| Abstract: | ABSTRACT: A t(ll;14)(p15;q11) was the sale chromosome abnormality observed in the malignant cells of a lO-year-old boy with acute leukemia. Morphologically, these cells were classified as L1 by the criteria of the French-American-British Working Group. Cytochemical analysis revealed that the leukemic cells were negative for Sudan Black B, periodic acid Schiff, and esterases, and positive for acid phosphatase. Immunophenotyping disclosed that the cells expressed a very immature antigenic profile [CD34 +, CD7 +, cytoplasmic CD3 +, membrane CD3 -, CD4 -, and CDS-]. In spite of very intensive chemotherapy, complete remission was never induced, and the child died of progressive disease. The relationship of this case to other reported cases of acute leukemia arising from immature pluripotent hematopoietic cells is discussed. |
| URI: | https://ninho.inca.gov.br/jspui/handle/123456789/13884 |
| ISSN: | 1873-4456 |
| Appears in Collections: | Hospital do Câncer I (HCI) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| CD7+, CD4CD8 acute leukemia with t(11;14)(p15;q11) in a child. 1991..pdf | 340.9 kB | Adobe PDF | View/Open |
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