Please use this identifier to cite or link to this item: https://ninho.inca.gov.br/jspui/handle/123456789/13884
Title: CD7 +, CD4-/CD8- Acute Leukemia with t(11;14)(p15;q11) in a Child
Authors: Valente, Aloísio Netto
Silva, Maria Luiza Macedo
Oliveira, Maria do Socorro Pombo de
Abdelhay, Eliana Saul Furquim Werneck
Bouzas, Luis Fernando da Silva
Laun, Lisselot
Ribeiro, Raul Corrêa
Keywords: Antígenos CD7
Antigens CD7
Antígenos CD4
CD4 Antigens
Antígenos CD8
CD8 Antigens
Leucemia-Linfoma de Células T do Adulto
Leukemia-Lymphoma Adult T-Cell
Chromosomes Human Pair 11
Cromossomos Humanos Par 14
Chromosomes, Human Pair 14
Cromossomos Humanos Par 11
Criança
Child
Issue Date: Oct-1991
Abstract: ABSTRACT: A t(ll;14)(p15;q11) was the sale chromosome abnormality observed in the malignant cells of a lO-year-old boy with acute leukemia. Morphologically, these cells were classified as L1 by the criteria of the French-American-British Working Group. Cytochemical analysis revealed that the leukemic cells were negative for Sudan Black B, periodic acid Schiff, and esterases, and positive for acid phosphatase. Immunophenotyping disclosed that the cells expressed a very immature antigenic profile [CD34 +, CD7 +, cytoplasmic CD3 +, membrane CD3 -, CD4 -, and CDS-]. In spite of very intensive chemotherapy, complete remission was never induced, and the child died of progressive disease. The relationship of this case to other reported cases of acute leukemia arising from immature pluripotent hematopoietic cells is discussed.
URI: https://ninho.inca.gov.br/jspui/handle/123456789/13884
ISSN: 1873-4456
Appears in Collections:Hospital do Câncer I (HCI)

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