Please use this identifier to cite or link to this item: https://ninho.inca.gov.br/jspui/handle/123456789/6763
Title: Cutoff values for HOMA-IR associated with metabolic syndrome in the Study of Cardiovascular Risk in Adolescents (ERICA Study)
Authors: Chissini, Rafaelle de Barros Caxiano
Kuschnir, Maria Cristina Caetano
Oliveira, Cecília Lacroix de
Giannini, Denise Tavares
Santos, Bráulio
Keywords: Resistência à Insulina
Insulin Resistance
Valores de Referência
Reference Values
Adolescente
Adolescent
Sexo
Sex
Brasil
Brazil
Issue Date: 2020
Publisher: Nutrition
Citation: CHISSINI, Rafaelle de Barros Caxiano et al. Cutoff values for HOMA-IR associated with metabolic syndrome in the Study of Cardiovascular Risk in Adolescents (ERICA Study). Nutrition, v. 71, p. 1-6, mar. 2020.
Abstract: The aim of this study was to determine the distribution of homeostatic model assessment of insulin resistance (HOMA-IR) values and define its cutoff associated with metabolic syndrome (MetS) in the partici pants of the Study of Cardiovascular Risk in Adolescents (Estudo de Risco Cardiovascular em Adolescentes). Methods: MetS was defined according to the International Diabetes Federation criteria. HOMA-IR values were calcu lated and tabulated by corresponding percentiles for age and sex. Receiver operating characteristic curves were con structed to identify the optimal cutoff values of HOMA-IR associated with MetS in the total population and by sex. Results: We evaluated 37 815 adolescents ages 12 to 17 y. The highest HOMA-IR medians were found among girls and boys ages 12 and 14 y, respectively. Thereafter, values tended to decrease with age. The optimal cutoff values of the HOMA-IR associated with MetS in the total population, in female adolescents, and in male adolescents were 2.80, 2.32, and 2.87, respectively. Insulin resistance was prevalent in 19.1% (95% confidence interval, 17.7 20.7) of the total population, and the prevalence was higher among girls and overweight Brazilian adolescents. Conclusions: These findings may serve as new reference points for detecting insulin resistance in Brazilian adolescents.
Description: p. 1-6.: il. p&b.
URI: http://sr-vmlxaph03:8080/jspui/handle/123456789/6763
ISSN: 0899-9007
Appears in Collections:Artigos de Periódicos da área de Nutrição



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