Please use this identifier to cite or link to this item: https://ninho.inca.gov.br/jspui/handle/123456789/7386
Title: Clinical and Molecular Properties of Human Immunodeficiency Virus-Related Diffuse Large B-Cell Lymphoma
Authors: Carvalho, Pedro Santos de
Leal, Fabio Eudes
Soares, Marcelo Alves
Keywords: Lymphoma, Non-Hodgkin
Linfoma não Hodgkin
Linfoma no Hodgkin
Lymphoma, Large B-Cell, Diffuse
Linfoma Difuso de Grandes Células B
Linfoma de Células B Grandes Difuso
Diffuse Large B-Cell Lymphoma
Linfoma Difuso de Células B Grandes
HIV
Issue Date: 2021
Publisher: Frontiers in Oncology
Abstract: Non-Hodgkin lymphoma is the most common malignancy affecting people living with HIV (PLWH). Among its several subtypes, diffuse large B-cell lymphoma (DLBCL) is an important manifestation within the HIV-infected compartment of the population. Since HIV is able to modulate B cells and promote lymphomagenesis through direct and indirect mechanisms, HIV-related DLBCL has specific characteristics. In this review, we address the clinical and molecular properties of DLBCL disease in the context of HIV infection, as well as the mechanisms by which HIV is able to modulate B lymphocytes and induce their transformation into lymphoma.
URI: http://sr-vmlxaph03:8080/jspui/handle/123456789/7386
ISSN: 2234-943X
Appears in Collections:Artigos de Periódicos da Pesquisa Experimental e Translacional



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