Please use this identifier to cite or link to this item: https://ninho.inca.gov.br/jspui/handle/123456789/8931
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dc.contributor.authorAraújo, Elaine Bortoleti de-
dc.contributor.authorPujatti, Priscilla Brunelli-
dc.contributor.authorCaldeira Filho, Jose de Souza-
dc.contributor.authorColturato, Maria Tereza-
dc.contributor.authorMuramoto, Emiko-
dc.contributor.authorNagamati, Lúcio Takeshi-
dc.contributor.authorCouto, Renata Martinussi-
dc.contributor.authorMengatti, Jair-
dc.contributor.authorSilva, Christiano Pereira-
dc.date.accessioned2022-07-12T12:10:37Z-
dc.date.available2022-07-12T12:10:37Z-
dc.date.issued2009-
dc.identifier.citationARAÚJO, Elaine Bortoleti de et al. A comparative study of 131I and 177Lu labeled somatostatin analogues for therapy of neuroendocrine tumours. Applied Radiation and Isotopes, v. 67, p. 227–233, 2009.-
dc.identifier.urihttp://sr-vmlxaph03:8080/jspui/handle/123456789/8931-
dc.descriptionp. 227–233.: il p&b. e color.-
dc.description.abstractThis work analysed the influence of the chelating group and radioligand on somatostatin analogues in vivo and in vitro properties. The presence of DOTA in the radioiodinated peptide produced a labeled analogue with similar blood kinetics and biodistribution to 177Lu-DOTATATE and with lower abdominal uptake than 131I-TATE. In addition, 131I-DOTATATE showed significative tumour uptake, despite not so persistent after 24 h. 131I-DOTATATE can represent a cost-effective alternative to lutetium labeled peptide for neuroendocrine tumours therapy.-
dc.publisherApplied Radiation and Isotopespt_BR
dc.subjectSomatostatinapt_BR
dc.subjectSomatostatinpt_BR
dc.subjectTumores Neuroendócrinospt_BR
dc.subjectNeuroendocrine Tumorspt_BR
dc.subjectTumores Neuroendocrinospt_BR
dc.subjectTerapia Molecular Dirigidapt_BR
dc.subjectTerapia de Alvo Molecularpt_BR
dc.subjectMolecular Targeted Therapypt_BR
dc.titleA comparative study of 131I and 177Lu labeled somatostatin analogues for therapy of neuroendocrine tumourspt_BR
dc.TypeArticlept_BR
Appears in Collections:Artigos de Periódicos da área de Farmácia



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