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https://ninho.inca.gov.br/jspui/handle/123456789/12262| Title: | Genetic diversity of human papillomavirus types 35, 45 and 58 in cervical cancer in Brazil |
| Authors: | Basto, Diogo Lisbôa Felix, Shayany Pinto Pinto, Laine Celestino Vidal, João Paulo Castello Branco Soares, Bruno Moreira Martins, Luís Felipe Leite Correa, Fla´via Miranda Montenegro, Raquel Carvalho Almeida, Liz Maria de Ponte, Vale´ria Barbosa Chaves, Cláudia Bessa Pereira Moreira, Miguel Angelo Martins |
| Keywords: | Neoplasias do Colo do Útero Uterine Cervical Neoplasms Papillomaviridae Neoplasias do Colo do Útero Uterine Cervical Neoplasms HPV35 HPV45 HPV58 HPV diversity |
| Issue Date: | 2017 |
| Publisher: | Arch Virol |
| Abstract: | In Brazil, most studies of intra-type variants of human papillomavirus (HPV) have focused on HPV16 and HPV18, but other high-risk HPV types have not been studied. Here, we report the prevalence of lineages and variants of HPV35, HPV45 and HPV58 in cervical cancers from the Amazonian and Southeast Brazilian regions. The most frequent sublineages were A1 for HPV35, B2 for HPV45, and A2 for HPV58. The Southeast region had a higher frequency of the B2 sublineage of HPV45, and for HPV35, the genetic and nucleotide sequence diversity were higher in the Southeast region, suggesting that regional factors are influencing the diversity and lineage prevalence. |
| URI: | https://ninho.inca.gov.br/jspui/handle/123456789/12262 |
| ISSN: | 1432-8798 |
| Appears in Collections: | Artigos de Periódicos da área de Pesquisa Populacional |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Genetic diversity of human papillomavirus types 35, 45 and 58 in cervical cancer in Brazil..pdf | 431.03 kB | Adobe PDF | View/Open |
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